Photo Credits: Sony Pictures Releasing

Zach Cregger’s Resident Evil could beat Alien: Romulus and Scream VI at the global box office. The upcoming horror movie is heading into theaters with strong early momentum ahead of its release next week.

BO tracker GlobalBoxOffice wrote on X (formerly Twitter), “Zach Cregger’s RESIDENT EVIL is now tracking for a $120M-$150M global debut next week. Pre-sales started in multiple countries this week. IMAX and other PLFs sales are doing extremely well overseas”.

Zach Cregger’s RESIDENT EVIL is now tracking for a $120M-$150M global debut next week.

Pre-sales started in multiple countries this week. IMAX and other PLFs sales are doing extremely well overseas. pic.twitter.com/hd0dC1I5RD

— Global Box Office (@GlobalBoxOffice) September 10, 2026

If the projection holds, Resident Evil would open above both recent horror hits worldwide. Alien: Romulus debuted with about $108.2 million globally in 2024, while Scream VI opened to roughly $67 million in 2023.

Zach Cregger’s Resident Evil brings the iconic video game franchise back to theaters

Resident Evil arrives in theaters on September 18, 2026, with Cregger directing and co-writing the movie with Shay Hatten. Sony Pictures describes it as an all-new story that reinvents the long-running Capcom franchise.

Austin Abrams stars as Bryan, a medical courier who becomes caught in a deadly outbreak. His delivery takes him into a chaotic night where survival becomes his only goal.

The story takes place alongside the events of Resident Evil 2 in 1998 Raccoon City. However, Bryan is an original character rather than one of the games’ established heroes. Cregger has also drawn inspiration from Resident Evil 4 and Resident Evil 7.

The director is also bringing elements from the games into the movie. Bryan has limited ammo and health, which adds more tension to his journey. Cregger wants viewers to feel the same pressure players face when their supplies run low.

The cast also includes Zach Cherry, Kali Reis, and Paul Walter Hauser. Resident Evil gives Cregger a chance to put his own spin on one of gaming’s biggest horror franchises. Its theatrical release will show how audiences respond to his take on the series.

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