Working from home blurs the line between what is work and what is the employee's personal life. This skew in work-life balance can have knock-on effects on the rest of your life if you're not careful. But how do you handle these types of situations? 

Well, CCing an upper manager who has a handle on these types of things should do the trick. This does, of course, rely on there being some leader in the organization with their head screwed on straight.